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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a290d9bd26d5a17ad5b7965de84f95c3b4a7ae5efcaba2362f1c6a2e77a5e754' 
  AND token = 'hS81WuS2IJ68re1ksLvOt7+DtCBcyPigl53bD2qgb4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}