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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '737980b77e27c5b1fdab0954e5d733235c109a8e43249f7e1928515bdd047b5c' 
  AND token = 'PBytd4b8uKTpf3zsHbhgN5dJ5RdwmwMC4GSEKMvWwxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}