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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072a55197ed33e6e367283a70d439bd8123e72c1fd8790f9c4808877422436a7' 
  AND token = 'pHz0wDQyGkW/9oZIVgM1znHMtH6qu9aPbE839MkuC6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}