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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6081680fce212e4505178326d7f6d1364ed3d7600af704729da6f638f0588dd' 
  AND token = 'H7ZOD/Cr9dKC8eNUYbqpkVZSHVQuqranH2pkYEv3zAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}