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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '384397d787172003810991630dd7f1845677edc36ab6738b69b93c5d0bc24085' 
  AND token = 'd4EGxHacz5yUvrB4QasfHq4P/GOSPYT9VQ/nmZmYDQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}