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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50dc9595838256ba5e13f76ef7ac25f679022b2f7157abe89b8ea10f9ee3cd77' 
  AND token = '0tHDFZdt6xjdvVUFBLk2LjzbHqQbLRm6Mm9LCOp7TkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}