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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe8198379782fac9a955dfd51f32207a2712c5d64f9e655cdfe34cdeadbf5e33' 
  AND token = 'et/Rx4iIS4tvNzk+HhTj+4c13mzXUSUOofhHHW8/KUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}