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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3728435fd8d1aa8f163aceaa2159a968b374967e288f1c3f3485b720efa9b66' 
  AND token = '9ee7eUpbFf+Ya6gS56z5vKT6RtFnnnoAZ1aqsOX4OcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}