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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20b7c6c62e05f8229a41dfebba289881b3822f4d6a674b1577ca354e9f6ec389' 
  AND token = 'A0i9PjoDPK2Y1N77NCa6MzpJFJtEX64b7A3Qrl10U3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}