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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd3d287978d0874a1b7d1f4b0a8e11394920678fcef10fb65dda63e3b5a36de1' 
  AND token = 'X/ms5362K51jkdyyzoaNXqsc/t3JJ48rOQ2wYj/dq64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}