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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32e72b639d3b6932811dbf250d01df0b2d1fed0ca83d5172a2772e32085f618f' 
  AND token = 'OlPlvh0D8Ugo+Dxy+OnST21gFjWxHI4N8XdzqW7Hi8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}