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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '542140c2e423cf1ca2a43703f226581efe736a0d33595d8292be55d361e86eef' 
  AND token = 'dEAf0+Yvg1sDft/CtsoG/+PPs9OSZOg7Y5W+iR66XYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}