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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2735992dd1b2fd97efcd57cd45716a27da741d51ce68fb735a9cf4fa4ab46b80' 
  AND token = 'NJhbD4WOHOIFtR/PAb3uYAf3MS7taiOAhxc56EF0j50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}