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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed20840c5a882a8ef228ed2289c3fba9a869b40063a1a1b6c722f089e80d5aa' 
  AND token = 'Nht6X3uEsuuM8xKKVVRP/8ddXqKezNPfD9Zcd6Ps5fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}