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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a3c7bccc79f9bc80886cd86871f55aec35929f4fddcd0c6ead68c50ad9300cf' 
  AND token = 'V7XDT8syoQZPLZlJycxeLa0Py5DEzUOQiJVboeDrYx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}