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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866474d76c1507ba4b76167bf3eb6ede26760b164f0bca95267d52018290b5ba' 
  AND token = 'lGU+Wts8w6ILCJH9A66jvxQ1uQALh70TPU+nvf1bvQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}