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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4024a3793bbcaa9a497ea66a54e885a52a7e9df8f61d44956b647a6a5d35a75f' 
  AND token = 'AeVUEPyk/tG6khAN1jsYlyIKpepP2FnnTGjymlIAxjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}