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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463d3e54db41a32dc5f4f668e7b7676e0e4477ad2c42e8524179827a115d4a3b' 
  AND token = 'qU1IhAvrJEf7sBCiV504c0okOLqP9vPc1dNZN6iMyZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}