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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e210e0dea53b1b332310363541e96cade5304b838cf03d910e88142b20e394d6' 
  AND token = 'T03A5be0tWFxygpdbj15r+WKJq7YDsZI9vatM4LLNLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}