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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0235f8a85a1d5af219b4505d9e5265bb42644d13d19619a0f524a6217a533a02' 
  AND token = 'MyjnL0UBPOk8TSfKPej5gPXrapVTi7vooqDGzXr/InU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}