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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9f389393d7475838c2775db11f434be5c459c1bdc46d3313bf53090fec483d9' 
  AND token = 'v4Ts73yoh4FlxwC4d4nVQJ5CTKkEwPq8y+jSuA4Q778=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}