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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef103e5d9206b36f72c3459e2edc9c14327283dbb5107af926ac554e87da472a' 
  AND token = 'SpnB/EJMCA3Z8UgB/erTB/HBerp07PMH65/EVv6fztI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}