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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96db8a9c84f69d916c3ec7d460d7a98f1a9a647ec045006860b41fb643892360' 
  AND token = 'QaiyfZL2k4xMCeKzplLAMryrAu31/mcQc3p+XbW43DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}