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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac93ffd206daf4c8f91fa67d1054396d141def9aaac811c8d9a5f82c2a801784' 
  AND token = 'V4Em20ca2QH4p9sJf7zJcETAQiVnw826NMORPUWcyiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}