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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331541dd678c0f4eee32c1c5c7fa83db4b46d407c9a5ff36a534e9c1049ee61f' 
  AND token = 'w0mRu2CaN4yj9mFdbMQwFoFa1jA1f3Bs1XCOW7qVxOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}