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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5617049d5c16bb33f4ef70ef208136d36b47a69aaf408e44a6a05ab5902257' 
  AND token = 'a33F+aA+HzqFBw6y66kKZXMZaE+PGgkERluCKu5gTkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}