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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72a3b2a61bd0f0d938a6e9009c87519bdfe6a2ab1073975d3467e32eb152d05' 
  AND token = '439Kw3Dq51JDx+/hgSyzgLgvQcL4WRzR3Az1UkFkTGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}