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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dce49f6c01240f6678801a5997bf016f5dc8d3780bcb2568ee7151725c0026c1' 
  AND token = '7BhrrJiW9/cvmqpTIE5wHjrRp1h377RrTY7iTbAObNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}