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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d5bdd2e8613630d913b61fd2b944fb473c74d1ce264bed8d288c49141e88731' 
  AND token = '5CrAmVh1TWMaY36c7sgkreEuwU1XmIJgeObEpt+lFPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}