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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c35025ab8438b4ff0fdd6ee02620a427358fbfa334a96b6d8d11b5f6ab89d489' 
  AND token = '5yxnF9qa0lWZlAu4+5bwuEEZr+uJndZ/WPvLfxZh5uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}