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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba605b4d6ce3534adbba5063c10bfbddc4509dbee7dab6b61484a39e194e630b' 
  AND token = 'aQpMTq24+GuGTyuHPPBS4uMjUM4HtACxE3K0y9rAhBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}