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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfa1443548606a84c87345309745d0e284e13722b225bba4313f7336e2ab20a5' 
  AND token = 'iASfxj5MYYaZP2sI3Wf08lAOJWCAyGylxf0mdocVTTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}