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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f04d5d7ec4930db2c849fd049f12cb32e76e793b9410cceeb04a1eaa64d45b' 
  AND token = 'OJ0rXIQzs6Uqc3eoc/NfsPR5cs+AtjPds4vxdByAFaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}