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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9adfaec8ba0b5fc9e175b0eb3852c6c339111322f6427c4c368d0b07ade4071b' 
  AND token = '9N+gn191GHfubDE3ISgupxFOFw0JUxLGD3JPNmSP/LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}