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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '082cdd41e22e545ecfb2376144af40fe99193c106b1abd2bbe05a283840be008' 
  AND token = '/ckQiK7U+OCO1aPkCLrfuQJg7K9jDBeYbRonV8rNFSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}