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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fcce5c8d63ee11abfe01f9123a27bf02aa4757558403d77996cc01cc05a8ac5' 
  AND token = '1VMT1Q881y/IOKrA9UdbxW6hmTZwC1yYMXqHp2QUwV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}