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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d6c0d06b845ec547d3e0395a9cbdc6f97f2aa53cb7640e2e3f35ce1f407766' 
  AND token = 'uyEgAaq9egZ8qNGTXZk2Ftlaq2Xs35oLgcW/pvoabb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}