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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9c0b3df434a6aa1bf1a0807c354f4960875f969fc09f0c218e213e980e67a69' 
  AND token = 'SeiK/rkGM35nxKy+BUkH3jADbuiUZ6iejkEDLhjPg8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}