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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653eef3770100846106bf58b9ce0ca3c35aa29ff8eded7e59b1c99cc5b0b68f4' 
  AND token = 'MN989mTd5ZEVnnszmO2Bg6oBeXHLMBDWMf/G2G29OQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}