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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92900fc6c597052dc61779682859a79cb130685c30aa249aa71cad073186a3b4' 
  AND token = 'oVBcdhcd5exUYgRDK/2y+uw7HKBIDmnrmjxkE4PHoms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}