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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f86e987d43b89b0e6c1cb304dc642dd9a47c584c18766d86c0566934e6e4d6a' 
  AND token = '7ORVFTbYHuLJFhesIQ/J4KsOB+jV5nGW3yfriMao8WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}