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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e795b057ada4d67f87a3a129f5b8298f62ba8e83ce5adab9a962b972b5a944e' 
  AND token = 'YopvtJ3giYeES30XrIIwimyO1W94NUe49bgXIvH5Xdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}