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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c3821d529753bd916cbe1ac300de73b4c5d40c80e260ddf881a4b08492c31eb' 
  AND token = 'H3FDnYIaC+XpdEl65Mswk7BXPJY8Vm9zA9ypSxD+hB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}