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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd596733402c4942ed652f7541283555a292e2090584e1b3b9da3382d274a12f8' 
  AND token = '+ccv0B7XSyaG1of1CTxKNsIHzdzI1tLHtWw7P3z4vB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}