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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19f44b9a24827d424efeef6fc0038a0a2f65e3d39fd44c43a73815abdf0cae85' 
  AND token = '5LqqneFAqAq51ML65elRtLyhcVRljGss5RqrX1pedGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}