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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26057b4469278f96e69c20a0e28b17a4899e96159e8f093688ae9279b79ae662' 
  AND token = 'QeUDO10GBAiiWKLOJXJOARTdtlqt89ugZcXorgZ7KYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}