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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a40687e0f5602950f659d55cc956cc42d32ef1f09fa995ba122c82707029148' 
  AND token = 'CsOoZtq8az9Z+2GoamfvT2UjbYv6bUnTigtoXpUAlSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}