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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744900fb6fb44527ea6594591351240735108bf469a8dae356e1d0addc7bffeb' 
  AND token = 'NJZKi5/Uv3+uO9KWvsA7QeVVEg6rN9EyfiRRJAUuGIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}