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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8322be2018c566582c824937c58a835d3f6373cca9342e74f2f4736ae458d2' 
  AND token = 'm2Q6NmatX3HpS8e96/YjW2GVNXVEaEuqTeZGRunDMT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}