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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8720b76649be31ab58e51509fdc7e8f8352a7aacf3941f0b1063198cb8439d2e' 
  AND token = 'P2xmGe27JASbh9G0Bc2nszzaAsHQgr/0bk634Gffew4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}